Interaction network and enrichment analysis of genes upregulated in RING1 KO
Canned Analysis
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General Information
AccessionDCA00037540
TitleInteraction network and enrichment analysis of genes upregulated in RING1 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between RING1 KO cells and control cells in the GV oocyte cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Pdia6|Vmn1r165|Vmn1r158|Gm13103|Npc1|Cphx3|Gm1821|Cyb5a|Rps20|Dnajc3|Obox5|Pdpn|Ddx11|Rn7sk|Gm10012|Tuba3b|Adam17|Fcf1|Shfm1|Gm15698|Rpa3|Nlrp4e|Pam16|Rps13|Zbed3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1763
Cell TypeGV oocyte
Gene Symbol (human)RING1
Gene Symbol (mouse)Ring1
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM568469, GSM568470, GSM568471
Perturbed SamplesGSM568472, GSM568473, GSM568474
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE23033
Gene Expression Omnibus
Polycomb function during oogenesis is required for mouse early embryonic development (germinal vesicle oocytes)
14
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