Interaction network and enrichment analysis of genes downregulated in IPMK KD
Canned Analysis
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General Information
AccessionDCA00037607
TitleInteraction network and enrichment analysis of genes downregulated in IPMK KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between IPMK KD cells and control cells in the cell line: Breast carcinoma cell line Cal51 cell type.
Analysis URLhttp://genemania.org/#/search/human/HIST1H4C|LASP1|H2AFZ|ATP5B|ID3|MT1F|CDC20|POLE3|PHGDH|RPS12|COX7C|MT1G|HSP90AA1|CALM2|MT1A|MT1E|RPL18|SLC25A5|TUBB|EEF1A1|DNAJC8|NDUFA1|TAGLN|ENO1|COX4I1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1813
Cell Typecell line: Breast carcinoma cell line Cal51
Gene Symbol (human)IPMK
Gene Symbol (mouse)Ipmk
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1204534, GSM1204535, GSM1204536
Perturbed SamplesGSM1204540, GSM1204541, GSM1204542
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE49658
Gene Expression Omnibus
Human inositol polyphosphate multikinase regulates transcript-selective nuclear mRNA export to preserve genome integrity
14
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