Interaction network and enrichment analysis of genes upregulated in IPMK KD
Canned Analysis
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General Information
AccessionDCA00037610
TitleInteraction network and enrichment analysis of genes upregulated in IPMK KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between IPMK KD cells and control cells in the cell line: Breast carcinoma cell line Cal51, samples were treated with DNA crosslinking reagent mitomycin C (MMC) for 24h prior to harvest cell type.
Analysis URLhttp://genemania.org/#/search/human/CCND1|CA2|TMSB10|SPP1|ATP6V0E1|RPS12|AP1S2|HINT1|POMP|RNASET2|EIF4A1|TXNDC12|TNNC1|MYL12B|MYL12A|HIGD1A|ANXA5|TPI1|NETO2|GDF15|LDHA|RCN1|PSMB7|TNFRSF21|ATP6V1A
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1814
Cell Typecell line: Breast carcinoma cell line Cal51, samples were treated with DNA crosslinking reagent mitomycin C (MMC) for 24h prior to harvest
Gene Symbol (human)IPMK
Gene Symbol (mouse)Ipmk
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1204537, GSM1204538, GSM1204539
Perturbed SamplesGSM1204543, GSM1204544, GSM1204545
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE49658
Gene Expression Omnibus
Human inositol polyphosphate multikinase regulates transcript-selective nuclear mRNA export to preserve genome integrity
14
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