Interaction network and enrichment analysis of genes downregulated in KLF13 KO
Canned Analysis
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General Information
AccessionDCA00037631
TitleInteraction network and enrichment analysis of genes downregulated in KLF13 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between KLF13 KO cells and control cells in the naive splenic CD8 T cells cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Nkg7|Rps11|Gm10925|Prf1|Gm12191|Rpl17|Rps14|Ldha|Hspa8|Rpl21|Rps6|Ly6c2|Rps27rt|Rps18|Npm1|Ms4a4c|Rpl9|Rn28s1|Hspe1|Cd53|Hnrnpk|Tfrc|Stk17b|Gm10653|Sidt1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:1821
Cell Typenaive splenic CD8 T cells
Gene Symbol (human)KLF13
Gene Symbol (mouse)Klf13
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM626977, GSM626978
Perturbed SamplesGSM626969, GSM626976
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE25502
Gene Expression Omnibus
KLF13 regulate memory-like CD8 T cells
7
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