Interaction network and enrichment analysis of genes upregulated in KDM5A KD
Canned Analysis
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General Information
AccessionDCA00037638
TitleInteraction network and enrichment analysis of genes upregulated in KDM5A KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between KDM5A KD cells and control cells in the cell line: ONS76 cell type: medulloblastoma cell type.
Analysis URLhttp://genemania.org/#/search/human/CXCL8|ID1|S100A2|PTX3|CXCL6|GJA1|STEAP1|IER3|TUBA1A|DKK1|PTGS2|AMIGO2|TNFRSF12A|S100A16|CYR61|CEBPB|F3|CSTA|KRT75|RPL39|FST|PRDX4|TFPI2|TMSB4XP8|CLDN1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1828
Cell Typecell line: ONS76 cell type: medulloblastoma
Gene Symbol (human)KDM5A
Gene Symbol (mouse)Kdm5a
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1065188, GSM1065189, GSM1065190
Perturbed SamplesGSM1065185, GSM1065186, GSM1065187
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43552
Gene Expression Omnibus
Expression profiling of human medulloblastoma cell line ONS76 upon siRNA-mediated knockdown of KDM5A/LSD1
7
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