Interaction network and enrichment analysis of genes downregulated in AGR2 KD
Canned Analysis
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General Information
AccessionDCA00037667
TitleInteraction network and enrichment analysis of genes downregulated in AGR2 KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between AGR2 KD cells and control cells in the pancreatic cancer cell line FA6 transiently transfected cell type.
Analysis URLhttp://genemania.org/#/search/human/ANP32B|TUBB|SLC25A6|RPS10|RPL41|PTHLH|APEX1|HMGN2|RPL21|SEC11A|TMSB4XP8|DYNLT1|ACTB|HDAC1|ACTG1|PTTG1|FAM96B|CWC15|PPP1CC|GARS|CCT7|RPLP0|AGR2|BZW1|RPLP0P6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1843
Cell Typepancreatic cancer cell line FA6 transiently transfected
Gene Symbol (human)AGR2
Gene Symbol (mouse)Agr2
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM314408, GSM314409, GSM314410
Perturbed SamplesGSM314405, GSM314406, GSM314407
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE12513
Gene Expression Omnibus
Genes regulated by AGR2 in pancreatic cancer cell lines FA6 and MiaPaCa2
14
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