Interaction network and enrichment analysis of genes upregulated in SMCHD1 KO
Canned Analysis
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General Information
AccessionDCA00037672
TitleInteraction network and enrichment analysis of genes upregulated in SMCHD1 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between SMCHD1 KO cells and control cells in the pre-B cells, day E17.5, C57BL/6 Eµ-Myc cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Rpl41|ND4|Mt1|Rpl32|Ndn|Rpl9|Rps29|COX2|Eif1|Hist1h2ap|Lgals1|Rps2|ND1|Cdkn1c|Cox4i1|Hist1h2af|CYTB|Erdr1|1500012F01Rik|Rplp1|Rps21|Rps5|Gm4832|Vpreb3|Rps3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1845
Cell Typepre-B cells, day E17.5, C57BL/6 Eµ-Myc
Gene Symbol (human)SMCHD1
Gene Symbol (mouse)Smchd1
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1004036, GSM1004038, GSM1004040
Perturbed SamplesGSM1004037, GSM1004039, GSM1004041
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE40879
Gene Expression Omnibus
The effect on gene expression of Smchd1 deletion in pre-B cells from E17.5 E-Myc embryos
7
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