Interaction network and enrichment analysis of genes upregulated in CDK8 knockdown
Canned Analysis
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General Information
AccessionDCA00037740
TitleInteraction network and enrichment analysis of genes upregulated in CDK8 knockdown
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between CDK8 knockdown cells and control cells in the unknown cell line stimulated with serum cell type.
Analysis URLhttp://genemania.org/#/search/human/SEMA3A|MIR622|BMP4|PVRL3|CD44|PLK2|KRT8|AKAP12|JAG1|ANXA2P2|S100A10|SLC2A1|PPP3CA|ANXA1|KRT18|RN7SK|TUBA1A|ANXA2|PRDX6|RBBP8|SOX4|TMSB4XP6|SMURF2|PDLIM5|ZDHHC2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1896
Cell Typeunknown cell line stimulated with serum
Gene Symbol (human)CDK8
Gene Symbol (mouse)Cdk8
Organismhuman
Perturbation Typeknockdown
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM475978, GSM475979, GSM475982, GSM475983
Perturbed SamplesGSM475980, GSM475981, GSM475984, GSM475985
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE19199
Gene Expression Omnibus
Expression data from serum-starved control and CDK8 depleted cells following serum stimulation
7
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