Interaction network and enrichment analysis of genes upregulated in FGFR1 drugactivation
Canned Analysis
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General Information
AccessionDCA00037790
TitleInteraction network and enrichment analysis of genes upregulated in FGFR1 drugactivation
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between FGFR1 drugactivation cells and control cells in the brown adipose tissue of ob/ob mice cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Lyz2|Mgp|Neat1|Cox8b|Col6a3|4931406C07Rik|Gm1821|Sepp1|Elovl3|Agpat2|Col6a1|Apoc1|Col6a2|Dusp1|Pgam1|Gcsh|Decr1|Bgn|Cox7a1|Spp1|Cyc1|Cd1d1|1110008P14Rik|Bnip3|Adipoq
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1928
Cell Typebrown adipose tissue of ob/ob mice
Gene Symbol (human)FGFR1
Gene Symbol (mouse)Fgfr1
Organismmouse
Perturbation Typedrugactivation
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM800590, GSM800591, GSM800592, GSM800593, GSM800594, GSM800595
Perturbed SamplesGSM800596, GSM800597, GSM800598, GSM800599, GSM800600, GSM800601
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE32316
Gene Expression Omnibus
FGFR1 target genes in brown adipose tissues
7
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