Interaction network and enrichment analysis of genes downregulated in GSK3B knockdown
Canned Analysis
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General Information
AccessionDCA00037799
TitleInteraction network and enrichment analysis of genes downregulated in GSK3B knockdown
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between GSK3B knockdown cells and control cells in the Panc-1 xenografts cell type.
Analysis URLhttp://genemania.org/#/search/human/BASP1|PSAP|DYNLL1|CRIP1|HSPA1A|TUBA1A|IFITM3|NCK2|CEBPB|CCL2|HSPA8|SSR4|LOC100093631|CD81|HOXC10|NGFRAP1|GDI1|MAGED1|NDUFA1|CAV1|PKD1P1|HMGB3|COX2|ABLIM1|C15orf48
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1934
Cell TypePanc-1 xenografts
Gene Symbol (human)GSK3B
Gene Symbol (mouse)Gsk3b
Organismhuman
Perturbation Typeknockdown
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM866688, GSM866689, GSM866690, GSM866691
Perturbed SamplesGSM866692, GSM866693, GSM866694
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE35351
Gene Expression Omnibus
GSK3B shRNA in Panc-1 xenografts
7
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