Interaction network and enrichment analysis of genes upregulated in JAK1 druginhibition
Canned Analysis
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General Information
AccessionDCA00037812
TitleInteraction network and enrichment analysis of genes upregulated in JAK1 druginhibition
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between JAK1 druginhibition cells and control cells in the BaF3 cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Ifitm1|Gm3150|Plgrkt|Slc18a2|Ap3s1|Pgam1|2410006H16Rik|Scin|Lgals1|Bnip3|D17H6S56E-5|Csf2rb|Asns|Cyb5r1|Rpl22l1|Ifitm3|Plac8|Psat1|Lbr|Slfn4|Cks2|BC094435|Ero1l|Mt2|Gm9790
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1941
Cell TypeBaF3
Gene Symbol (human)JAK1
Gene Symbol (mouse)Jak1
Organismmouse
Perturbation Typedruginhibition
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM940262, GSM940263, GSM940264
Perturbed SamplesGSM940268, GSM940269, GSM940270
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38335
Gene Expression Omnibus
JAK2 Naive and Persitent Murine BaF3 cells infected with MPLW515L
14
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