Interaction network and enrichment analysis of genes upregulated in DES depletion (at 12-14 month old)
Canned Analysis
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General Information
AccessionDCA00037862
TitleInteraction network and enrichment analysis of genes upregulated in DES depletion (at 12-14 month old)
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between DES depletion (at 12-14 month old) cells and control cells in the tibialis anterior muscle cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Eef1a2|Myh2|Myoz2|Csrp3|Sepw1|Nrap|Pkm|Psmb7|Sqstm1|Actn2|Bex1|Serpinb6a|Tmem38a|Pygm|Mybph|Psmd6|Rplp0|Lmcd1|Got2|Synpo2|Tpm2|Got1|Smtnl1|H19|Atp2a1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsolomoniyi
CREEDS IDgene:3048
Cell Typetibialis anterior muscle
Gene Symbol (human)DES
Gene Symbol (mouse)Des
Organismmouse
Perturbation Typedepletion (at 12-14 month old)
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM848136, GSM848137, GSM848138, GSM848139
Perturbed SamplesGSM848146, GSM848147, GSM848148, GSM848149
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE34388
Gene Expression Omnibus
Desmin deficiency effect on young and adult skeletal muscles
14
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