Interaction network and enrichment analysis of genes upregulated in AKT2 knockout
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00037868
TitleInteraction network and enrichment analysis of genes upregulated in AKT2 knockout
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between AKT2 knockout cells and control cells in the heart cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Hspb6|Tcap|Ech1|Crip2|Tnni3|Tnnt2|Ndufa13|Myl3|Lgals1|Gm1821|LOC100505088|Hrc|Cox6a2|LOC100048117|Asb2|Pln|Ndrg4|Mdh2|Hspb7|Etfb|Uqcrc1|Ivd|Aco2|Myl2|Hspa1b
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1983
Cell Typeheart
Gene Symbol (human)AKT2
Gene Symbol (mouse)Akt2
Organismmouse
Perturbation Typeknockout
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM472351, GSM472352, GSM472353
Perturbed SamplesGSM472350, GSM472354, GSM472355
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE19079
Gene Expression Omnibus
Myocardial expression data from wild-type and akt2-/- mice
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.