Interaction network and enrichment analysis of genes upregulated in MET activemutant
Canned Analysis
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General Information
AccessionDCA00037896
TitleInteraction network and enrichment analysis of genes upregulated in MET activemutant
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between MET activemutant cells and control cells in the MEFs cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Anxa3|Hmga1|Hmga2|Prmt8|BC005512|Kif2c|Cep55|Nek2|D14Ertd670e|Gsto1|Ndc80|2700099C18Rik|Fhl2|Plk1|Anln|Ttk|Spag5|Cpne1|Aurka|Nuf2|Cdc25c|Cdc20|Bub1|Anxa1|D14Ertd500e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:2004
Cell TypeMEFs
Gene Symbol (human)MET
Gene Symbol (mouse)Met
Organismmouse
Perturbation Typeactivemutant
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM285955, GSM285956, GSM285957, GSM285958, GSM285969, GSM285970, GSM285971, GSM285972
Perturbed SamplesGSM285959, GSM285960, GSM285961, GSM285962, GSM285973, GSM285974, GSM285975, GSM285976
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11319
Gene Expression Omnibus
Met mutations in MEFs
7
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