Interaction network and enrichment analysis of genes downregulated in GPLD1 OE
Canned Analysis
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General Information
AccessionDCA00037929
TitleInteraction network and enrichment analysis of genes downregulated in GPLD1 OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between GPLD1 OE cells and control cells in the Hepatoma HepG2 cells cell type.
Analysis URLhttp://genemania.org/#/search/human/RPS2|RPL37|IGFBP1|MIR1244-2|RPS24|MORF4L2|SLC38A2|RPL13|RPS20|H1F0|RPLP0|RPS27L|RPL19|CTGF|RPS27|RPL13AP5|ATP5E|PPIB|UBC|HINT1|SLC39A14|LAPTM4A|PSMA6|HSPE1|PABPC3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:203
Cell TypeHepatoma HepG2 cells
Gene Symbol (human)GPLD1
Gene Symbol (mouse)Gpld1
Organismhuman
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM106836, GSM106837, GSM106838, GSM106839, GSM106844, GSM106845, GSM106846, GSM106847
Perturbed SamplesGSM106840, GSM106841, GSM106842, GSM106843, GSM106848, GSM106849, GSM106850, GSM106851
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE4731
Gene Expression Omnibus
Glycosylphosphatidylinositol-specific phospholipase D overexpression effect on hepatoma cells: time course
21
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