Interaction network and enrichment analysis of genes downregulated in TET1 KD
Canned Analysis
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General Information
AccessionDCA00038035
TitleInteraction network and enrichment analysis of genes downregulated in TET1 KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between TET1 KD cells and control cells in the mesc_v6.5 cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Trh|Mt1|Hist1h2ap|Tet1|Gpx1|Nme1|Ifitm3|Polr2l|Srm|Pcbp1|Gja1|Dppa5a|Fth1|Psma2|Rpl41|Sgk1|Lgals1|CYTB|Morf4l2|S100a11|Zyx|Sssca1|Hint1|Odc1|Pcbp4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2146
Cell Typemesc_v6.5
Gene Symbol (human)TET1
Gene Symbol (mouse)Tet1
Organismmouse
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM662485, GSM662486, GSM662487
Perturbed SamplesGSM662488, GSM662489, GSM662490
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE26900
Gene Expression Omnibus
Effect of Tet1-knockdown on gene expression in mouse ES cells cultured in ES and TS cell culture conditions
7
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