Interaction network and enrichment analysis of genes upregulated in EOMES KO
Canned Analysis
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General Information
AccessionDCA00038038
TitleInteraction network and enrichment analysis of genes upregulated in EOMES KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between EOMES KO cells and control cells in the E14dot5_neocortex cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Ebf3|Dcc|Hsp90aa1|Actg1|Stmn2|Crabp1|Cacna2d1|Lhx2|Nhlh1|Vim|Tcf4|Zfp521|Pdzrn3|Dusp4|Nrp1|Dpysl2|Tubb3|Asic1|Uba1|Dach1|Gpm6b|Meg3|Btg1|Hnrnpk|Nell2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2147
Cell TypeE14dot5_neocortex
Gene Symbol (human)EOMES
Gene Symbol (mouse)Eomes
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1061846, GSM1061847, GSM1061849, GSM1061850, GSM1061851
Perturbed SamplesGSM1061845, GSM1061848, GSM1061852
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE43387
Gene Expression Omnibus
The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map
7
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