Interaction network and enrichment analysis of genes downregulated in NFE2L2 KO
Canned Analysis
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General Information
AccessionDCA00038047
TitleInteraction network and enrichment analysis of genes downregulated in NFE2L2 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between NFE2L2 KO cells and control cells in the neonate_P3_lung cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Scgb3a1|Scgb3a2|Myl7|Cbr2|Actc1|Ear12|Ear2|Aldh1a1|Hc|Gm3601|Tnnc1|Tubb5|Ear3|Cyp2f2|Cox6b1|Gm4076|Ftl2|LOC100048117|Atp5h|Gapdh|Gpx1|Retnla|Trf|H19|Ahsp
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2152
Cell Typeneonate_P3_lung
Gene Symbol (human)NFE2L2
Gene Symbol (mouse)Nfe2l2
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM734367, GSM734368, GSM734369
Perturbed SamplesGSM734388, GSM734389, GSM734390
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29632
Gene Expression Omnibus
Effect of Nrf2 deletion in postnatal lung development and BPD phenotype in newborn mice
7
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