Interaction network and enrichment analysis of genes downregulated in FOXA2 KO
Canned Analysis
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General Information
AccessionDCA00038071
TitleInteraction network and enrichment analysis of genes downregulated in FOXA2 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between FOXA2 KO cells and control cells in the P15_lung cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Cbr2|Hp|Igfbp2|BC094435|Tppp3|Adh1|Gdpd3|Scgb3a2|Cyp2f2|Sept4|Ctla2a|Ager|Erdr1|G0s2|Aplnr|Clk1|Pcolce2|Hpgd|Inmt|Icam1|Tuba1a|Tnnc2|Aqp1|Akap2|Postn
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2166
Cell TypeP15_lung
Gene Symbol (human)FOXA2
Gene Symbol (mouse)Foxa2
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM476005, GSM476007, GSM476008
Perturbed SamplesGSM476009, GSM476010, GSM476011
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19204
Gene Expression Omnibus
Foxa2 programs Th2-cell mediated innate immunity in the developing lung.
7
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