Interaction network and enrichment analysis of genes downregulated in RNF2 VR
Canned Analysis
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General Information
AccessionDCA00038079
TitleInteraction network and enrichment analysis of genes downregulated in RNF2 VR
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between RNF2 VR cells and control cells in the mouse_embryonic_stem_cell cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Tuba1a|Ifitm1|Chchd10|Lefty1|Gsta4|Ddit4|Trh|Fbxo15|Ifitm2|Erdr1|Slc2a1|Actg1|LOC100044627|Pfn1|Sox2|Chchd2|Phc1|Sumo2|Bex1|Nme2|Nhp2|Gpx4|Hint1|Trim28|Rps27a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2170
Cell Typemouse_embryonic_stem_cell
Gene Symbol (human)RNF2
Gene Symbol (mouse)Rnf2
Organismmouse
Perturbation TypeVR
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM472235, GSM472236, GSM472237
Perturbed SamplesGSM472238, GSM472239, GSM472240
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19076
Gene Expression Omnibus
Expression data from wild type, Ring1B-/-, Eed-/-, and Ring1B/Eed double deficient mouse ES cells
7
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