Interaction network and enrichment analysis of genes downregulated in CDKN1B KO
Canned Analysis
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General Information
AccessionDCA00038087
TitleInteraction network and enrichment analysis of genes downregulated in CDKN1B KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between CDKN1B KO cells and control cells in the 3T3 cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Ptma|Rps5|Rps27rt|Pcna|Gm10260|Rps29|Rps26|Rpl17-ps10|Rps19|Rps3a2|Gapdh|Lxn|Smc4|LOC100044627|LOC100048117|Ppia|Psma2|Lig1|LOC100048552|Rplp2|Plac8|Fth1|H19|Rpl13|Gm6793
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2179
Cell Type3T3
Gene Symbol (human)CDKN1B
Gene Symbol (mouse)Cdkn1b
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM231384, GSM231409, GSM231417
Perturbed SamplesGSM231405, GSM231414, GSM231425
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE9161
Gene Expression Omnibus
Expression profiling of cyclin D1 splice variants cyclin D1a and D1b in mouse 3T3 cells.
7
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