Interaction network and enrichment analysis of genes upregulated in SETDB1 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00038120
TitleInteraction network and enrichment analysis of genes upregulated in SETDB1 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between SETDB1 KO cells and control cells in the ES cells cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Krt18|Lgals1|Krt8|Serpine1|Lgals3|Tagln|S100a11|Krt7|S100a6|Slc2a1|H19|Cldn4|Cstb|BC094435|Krt19|Csrp1|Rhox6|Anxa5|Rhox9|Tpm4|Bnip3|Ngfrap1|Acta1|Cnn2|Anxa3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:2205
Cell TypeES cells
Gene Symbol (human)SETDB1
Gene Symbol (mouse)Setdb1
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM707696, GSM707697, GSM707698
Perturbed SamplesGSM707699, GSM707700, GSM707701
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE28593
Gene Expression Omnibus
KMT1E Mediated H3K9 Methylation Is Required for the Maintenance of Embryonic Stem Cells by Repressing Trophectoderm Differentiation
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.