Interaction network and enrichment analysis of genes upregulated in GATA6 KO
Canned Analysis
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General Information
AccessionDCA00038158
TitleInteraction network and enrichment analysis of genes upregulated in GATA6 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between GATA6 KO cells and control cells in the tissue resident peritoneal macrophages cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Fcna|F13a1|Ccl6|Cbr2|Folr2|Sepp1|Mrc1|Gstp1|Ccl9|Lyve1|Retnla|Pltp|Fth1|Hal|Actg1|Crip1|Serpinb6a|Slfn4|Marco|Ltc4s|Snx2|Kctd12|Anxa5|Gm8615|Gm14085
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2225
Cell Typetissue resident peritoneal macrophages
Gene Symbol (human)GATA6
Gene Symbol (mouse)Gata6
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1143766, GSM1143767, GSM1143768
Perturbed SamplesGSM1143763, GSM1143764, GSM1143765
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47049
Gene Expression Omnibus
Expression data from wild type and Gata6-deficient tissue resident peritoneal macrophages
7
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