Interaction network and enrichment analysis of genes upregulated in CTNNB1 KO
Canned Analysis
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General Information
AccessionDCA00038200
TitleInteraction network and enrichment analysis of genes upregulated in CTNNB1 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between CTNNB1 KO cells and control cells in the liver tumor tissue cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Apoa4|Oat|Gstm2|Ly6d|Glul|Ephx1|H19|Rdh9|Grina|Uba52|Gulo|Rpl39|Cstb|Hbb-bs|Rps12|S100a10|Rps14|Csrp2|Idh2|Cyb5a|Hist1h1c|Slc22a1|Cyp2a5|Aprt|Pon1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:2249
Cell Typeliver tumor tissue
Gene Symbol (human)CTNNB1
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1067299, GSM1067300, GSM1067301, GSM1067302
Perturbed SamplesGSM1067303, GSM1067304, GSM1067305, GSM1067306
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43628
Gene Expression Omnibus
Activation of beta-catenin in hepatocellular carcinoma (mouse Ctnnb1 knockout)
7
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