Interaction network and enrichment analysis of genes downregulated in FTO KD
Canned Analysis
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General Information
AccessionDCA00038315
TitleInteraction network and enrichment analysis of genes downregulated in FTO KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between FTO KD cells and control cells in the Flp-Inâ???????¢ 293 T-Rex cell type.
Analysis URLhttp://genemania.org/#/search/human/RPL26|RPS14P3|NGFRAP1|HIST1H4C|LIN28B|MYL12B|RPL7L1|RPS2|MMADHC|FTL|HSP90AA1|PSMA4|CKS2|GJA1|DEGS1|TRIAP1|EEF1A1|PSMA6|NAP1L1|CS|MRPS21|FTO|SRP19|NPC2|WDR82
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2335
Cell TypeFlp-Inâ???????¢ 293 T-Rex
Gene Symbol (human)FTO
Gene Symbol (mouse)Fto
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM838203, GSM838205
Perturbed SamplesGSM838202, GSM838204
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE33870
Gene Expression Omnibus
Effect of FTO overexpression and knockdown on transcriptome of HEK293 cells
21
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