Interaction network and enrichment analysis of genes upregulated in WNT1 OE
Canned Analysis
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General Information
AccessionDCA00038350
TitleInteraction network and enrichment analysis of genes upregulated in WNT1 OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between WNT1 OE cells and control cells in the A375 melanoma cell-line cell type.
Analysis URLhttp://genemania.org/#/search/human/TMSB4XP8|TGFBI|H3F3AP4|TMSB10|MMP1|S100A4|COL6A3|RPL32|TUBA1A|CSRP2|CTHRC1|COX2|DCAF6|SRP9|COX1|LGALS1|MLLT11|RPSA|NGFRAP1|FABP5|EEF1B2|NTS|ARF4|CDK2AP1|NDUFA12
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2355
Cell TypeA375 melanoma cell-line
Gene Symbol (human)WNT1
Gene Symbol (mouse)Wnt1
Organismhuman
Perturbation TypeOE
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM656286, GSM656287, GSM656288, GSM656289
Perturbed SamplesGSM656290, GSM656291, GSM656292
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE26656
Gene Expression Omnibus
Gene expression profiles of Wnt-1 overexpressing melanoma
14
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