Interaction network and enrichment analysis of genes upregulated in ZBTB7A KO

General Information

Accession	DCA00038394
Title	Interaction network and enrichment analysis of genes upregulated in ZBTB7A KO
Description	The analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between ZBTB7A KO cells and control cells in the strain/background: C57BL/6 genotype/variation: Zbtb7a Flox/Flox Mx1-Cre+ (LRF homozygous knockout) age: 4 weeks cell type: FACS-sorted LT-HSCs (LSK IL7Ra-Flt3-CD150+CD48-) time point: 9 days after 1st pIpC injection Treatment protocol LT-HSCs were FACS-sorted from three Lrf knockout (Zbtb7a Flox/Flox Mx1-Cre+) and two control (Zbtb7a Flox/+ Mx1-Cre+) mice, nine days after the first pIpC injection. pIpC (250Î¼g) was injected twice to induce Cre recombinase. cell type.
Analysis URL	http://genemania.org/#/search/mouse/Ermap\|Hba-x\|Car2\|H19\|Ahsp\|BC094435\|Plac8\|Hbb-bh1\|Hspd1\|Hemgn\|A730098P11Rik\|Hnrnpu\|Cacybp\|Rps11\|Glrx5\|Rps12\|Chchd2\|Gm6453\|Hspa8\|Gm7536\|Isg20\|Hsp90ab1\|Rps27a\|Snhg8\|Abcb4
Upload Date	September 20, 2017
Uploader	maayanlab

Metadata

Analysis Curator	gszeto
CREEDS ID	gene:2380
Cell Type	strain/background: C57BL/6 genotype/variation: Zbtb7a Flox/Flox Mx1-Cre+ (LRF homozygous knockout) age: 4 weeks cell type: FACS-sorted LT-HSCs (LSK IL7Ra-Flt3-CD150+CD48-) time point: 9 days after 1st pIpC injection Treatment protocol LT-HSCs were FACS-so
Gene Symbol (human)	ZBTB7A
Gene Symbol (mouse)	Zbtb7a
Organism	mouse
Perturbation Type	KO