Interaction network and enrichment analysis of genes downregulated in NR2E3 Ectopic expression - (NRL null retinas expressing NR2E3)
Canned Analysis
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General Information
AccessionDCA00038399
TitleInteraction network and enrichment analysis of genes downregulated in NR2E3 Ectopic expression - (NRL null retinas expressing NR2E3)
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between NR2E3 Ectopic expression - (NRL null retinas expressing NR2E3) cells and control cells in the Nrl-/- retina ( NRL - neural retinal leucine zipper - NULL Retinas) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Gnat2|Ccdc136|Pde6c|Arr3|Pde6h|Kcne2|Fam19a3|Guca1a|Opn1sw|Elovl5|Gnb3|Smim13|Guk1|Agpat9|Tmbim6|Smug1|BC094435|Cdhr1|Hnrnph3|Fabp7|Rpl4|Egr1|Luc7l3|Laptm4b|Dusp22
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2384
Cell TypeNrl-/- retina ( NRL - neural retinal leucine zipper - NULL Retinas)
Gene Symbol (human)NR2E3
Gene Symbol (mouse)Nr2e3
Organismmouse
Perturbation TypeEctopic expression - (NRL null retinas expressing NR2E3)
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM92610, GSM92611, GSM92612, GSM92613
Perturbed SamplesGSM121242, GSM121249, GSM121315, GSM121316
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE5338
Gene Expression Omnibus
Photoreceptor-specific nuclear receptor NR2E3 ectopic expression effect on NRL null retinas
7
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