Interaction network and enrichment analysis of genes downregulated in NR0B2 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00038417
TitleInteraction network and enrichment analysis of genes downregulated in NR0B2 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between NR0B2 KO cells and control cells in the tissue: liver (SHP uncertain if it is NR0B2 or PTPN6) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Cyp2a5|Cyp2f2|C9|Nudt7|LOC100048884|Mup19|Pebp1|Cyp2a12|Cyp2c29|Inmt|Igfbp2|Hpd|Cyp2c54|Nnmt|Cyp7b1|Cyp2c37|G0s2|Ces1c|Ces1f|Gstp1|Cyp2c50|Aox3|Serpina1b|Ephx1|Apoc3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2398
Cell Typetissue: liver (SHP uncertain if it is NR0B2 or PTPN6)
Gene Symbol (human)NR0B2
Gene Symbol (mouse)Nr0b2
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1001306, GSM1001307
Perturbed SamplesGSM1001308, GSM1001309
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40775
Gene Expression Omnibus
Microarray analysis of genes regulated by SHP in wild-type and ob/ob mice.
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.