Interaction network and enrichment analysis of genes downregulated in MIR122 KO
Canned Analysis
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General Information
AccessionDCA00038433
TitleInteraction network and enrichment analysis of genes downregulated in MIR122 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between MIR122 KO cells and control cells in the background strain: B6/129, tissue: liver/tumor cell type.
Analysis URLhttp://genemania.org/#/search/mouse/LOC100048884|Mup19|2810007J24Rik|Gstp1|Serpina3k|Ces3a|Cyp2c70|Akr1c6|C8a|Mug1|Ugt2b1|Cyp2c50|Wfdc21|Arg1|Apcs|C9|Plg|Cyp2f2|Gnmt|Hsd11b1|Mug2|Pigr|Pon1|Hc|Serpina1b
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2408
Cell Typebackground strain: B6/129, tissue: liver/tumor
Gene Symbol (human)MIR122
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM781673, GSM781674, GSM781675, GSM781676, GSM781677
Perturbed SamplesGSM781678, GSM781679, GSM781680, GSM781681, GSM781682, GSM781683, GSM781684, GSM781685
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31453
Gene Expression Omnibus
Genome-wide analysis of gene expression patterns in the liver tumors of mir-122 knockout mice
7
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