Interaction network and enrichment analysis of genes downregulated in GATA3 OE
Canned Analysis
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General Information
AccessionDCA00038637
TitleInteraction network and enrichment analysis of genes downregulated in GATA3 OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between GATA3 OE cells and control cells in the R1 embryonic stem cell line cell type.
Analysis URLhttp://genemania.org/#/search/mouse/H19|Tmsb4x|S100a11|Trh|Igfbp2|Pmp22|S100a6|A730098P11Rik|Tuba1a|Cd81|Ier3|Gm4076|Rcn3|Slc2a1|Fat1|Cdh1|Mdk|Gpx3|Anxa3|Col18a1|Lgals1|Ccng1|Pdpn|Rps19|Cldn6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDgene:2531
Cell TypeR1 embryonic stem cell line
Gene Symbol (human)GATA3
Gene Symbol (mouse)Gata3
Organismmouse
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM325450, GSM325451, GSM325452, GSM325453, GSM325454, GSM325455, GSM325459
Perturbed SamplesGSM325456, GSM325457, GSM325458
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE12999
Gene Expression Omnibus
Cdx2 and Gata3 overexpression effect on R1 embryonic stem cell line
7
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