Interaction network and enrichment analysis of genes downregulated in CREM KO
Canned Analysis
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General Information
AccessionDCA00038669
TitleInteraction network and enrichment analysis of genes downregulated in CREM KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between CREM KO cells and control cells in the testis cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Wdr19|Prm1|Smcp|Tnp2|Acsl1|Galntl5|Spz1|Slc16a7|Oaz3|Hils1|Odf1|Spata18|Tmco2|Dnajc5b|Cabs1|Stard10|Gpd2|Tnp1|Glrx2|Atp1b3|Atp1a4|1700029H14Rik|Reep6|4933411K16Rik|Nt5c1b
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2559
Cell Typetestis
Gene Symbol (human)CREM
Gene Symbol (mouse)Crem
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM732639, GSM732640, GSM732642, GSM732643, GSM732644
Perturbed SamplesGSM732637, GSM732638, GSM732641, GSM732645, GSM732646
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29593
Gene Expression Omnibus
The effect of Crem absence on gene expression in mouse testis.
7
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