Interaction network and enrichment analysis of genes downregulated in OVOL1 KO
Canned Analysis
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General Information
AccessionDCA00038671
TitleInteraction network and enrichment analysis of genes downregulated in OVOL1 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between OVOL1 KO cells and control cells in the isolated keratinocytes from mouse skin cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Kdm5d|Ddx3y|Eif2s3y|Lce1e|Kprp|Crct1|Sprr2i|Sprr2e|Fscn1|Acta2|Lce1a1|F3|Sprr2d|Igfbp2|Chac1|Fn1|Asns|Krt7|Hspa5|Fads3|Dusp14|Nupr1|Trex2|Hmox1|Dhrs1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2560
Cell Typeisolated keratinocytes from mouse skin
Gene Symbol (human)OVOL1
Gene Symbol (mouse)Ovol1
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1329071, GSM1329072
Perturbed SamplesGSM1329073, GSM1329074
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE55071
Gene Expression Omnibus
Expression data from calcium-induced isolated keratinocytes from mouse skin with or without Ovol1 and Ovol2 expression
7
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