Interaction network and enrichment analysis of genes downregulated in HMGA2 OE
Canned Analysis
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General Information
AccessionDCA00038677
TitleInteraction network and enrichment analysis of genes downregulated in HMGA2 OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between HMGA2 OE cells and control cells in the strain: C57BL/6J cell type: bone marrow, c-Kit+Lin-Sca-1+ (KLS) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Rnu3a|Hist1h2bn|Hist1h2ao|Hist1h4m|Hist1h2br|Ngp|Hist1h4d|Igkv6-14|Tyrobp|Snrpd3|Igkv10-96|Arhgdib|Rn7sk|Hba-a2|Tmsb10|Hist2h2aa2|Dynlrb1|Rn18s|Max|Snord104|Gapdh|Gm6981|Igj|AY036118|Gpx1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2563
Cell Typestrain: C57BL/6J cell type: bone marrow, c-Kit+Lin-Sca-1+ (KLS)
Gene Symbol (human)HMGA2
Organismmouse
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM592264, GSM592269
Perturbed SamplesGSM592262, GSM592266
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE24071
Gene Expression Omnibus
HMGA2 overexpression
14
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