Interaction network and enrichment analysis of genes downregulated in KDR KD
Canned Analysis
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General Information
AccessionDCA00038729
TitleInteraction network and enrichment analysis of genes downregulated in KDR KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between KDR KD cells and control cells in the glioma cells cell type.
Analysis URLhttp://genemania.org/#/search/human/RPL35|HSPB1|EEF1A2|ANP32B|FLOT2|CCND1|PTRF|SLC25A39|OAZ1|PHGDH|SUMO3|AIF1L|EIF3E|VIM|DNMT1|UCHL1|DDX39A|TUBB4B|TKT|FSCN1|C7orf50|MARCKS|PIK3R2|GLIPR2|PITX1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
CREEDS IDgene:2589
Cell Typeglioma cells
Gene Symbol (human)KDR
Gene Symbol (mouse)Kdr
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1498939, GSM1498940, GSM1498941
Perturbed SamplesGSM1498942, GSM1498943, GSM1498944
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE61178
Gene Expression Omnibus
LN-308/U-138MG shVEGFR-2 knock-down analysis
7
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