Interaction network and enrichment analysis of genes upregulated in PSMC4 KO
Canned Analysis
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General Information
AccessionDCA00038734
TitleInteraction network and enrichment analysis of genes upregulated in PSMC4 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between PSMC4 KO cells and control cells in the skeletal muscle cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Sln|H19|Mt1|Gstp1|Hspb1|Rpl19|Fabp3|Rps20|Uchl1|Fth1|Sqstm1|Mustn1|Rpl11|Rplp0|Hsp90ab1|Rpl41|Col3a1|Psmd4|Psmd1|Thbs4|Cryab|Rps14|Psmb6|Psmb2|Rps27a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2594
Cell Typeskeletal muscle
Gene Symbol (human)PSMC4
Gene Symbol (mouse)Psmc4
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM857256, GSM857257, GSM857258
Perturbed SamplesGSM857253, GSM857254, GSM857255
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34896
Gene Expression Omnibus
Muscle specific proteasome deficient mice
7
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