Interaction network and enrichment analysis of genes downregulated in KDM1B KD
Canned Analysis
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General Information
AccessionDCA00038753
TitleInteraction network and enrichment analysis of genes downregulated in KDM1B KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between KDM1B KD cells and control cells in the HeLa cells cell type.
Analysis URLhttp://genemania.org/#/search/human/INHBB|OAZ1|BASP1|COX1|BZW1|SDHA|ASS1|UBC|CD55|EIF4A3|ATF4|SDHAP1|KANK4|HSP90AA1|RPS6|TUBB|RBBP7|CKS2|CPS1|FTH1P5|SGK1|GARS|CEBPB|RPL3|CISD1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlkwhite
CREEDS IDgene:2611
Cell TypeHeLa cells
Gene Symbol (human)KDM1B
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM564835, GSM564836
Perturbed SamplesGSM564833, GSM564834
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE22859
Gene Expression Omnibus
Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating H3K4me2 methylation (Affymetrix)
7
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