Interaction network and enrichment analysis of genes downregulated in IL22 KO
Canned Analysis
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General Information
AccessionDCA00038799
TitleInteraction network and enrichment analysis of genes downregulated in IL22 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between IL22 KO cells and control cells in the Ileum cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Reg3g|Saa1|Dmbt1|Reg3b|AI747448|Muc13|Cd38|Gm15315|Car4|Gpx2|Ceacam2|Defa22|B3gnt7|Spink3|Ly6a|Prr13|Plet1|Tifa|Plac8|Muc3|Tm4sf20|Hk2|Sprr2a2|Bcl2l15|Ceacam1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCarolet
CREEDS IDgene:2663
Cell TypeIleum
Gene Symbol (human)IL22
Gene Symbol (mouse)Iltifb
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1598152, GSM1598153, GSM1598154, GSM1598155, GSM1598156
Perturbed SamplesGSM1598157, GSM1598158, GSM1598159, GSM1598160, GSM1598161
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE65472
Gene Expression Omnibus
Identification of IL-22 regulated genes in the ileum after infection with Toxoplasma gondii
7
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