Interaction network and enrichment analysis of genes downregulated in POR DELETION
Canned Analysis
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General Information
AccessionDCA00038805
TitleInteraction network and enrichment analysis of genes downregulated in POR DELETION
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between POR DELETION cells and control cells in the Liver from male 3 month old cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Mug-ps1|Cyp4v3|Pigr|Cyp2d26|Hsd11b1|Gstp1|Hba-a1|Mug2|Hsd3b5|Ptms|C9|Cyp2f2|Ahsg|C4a|Tdo2|Ces1c|Mug1|Cyp2c69|Ttr|C3|Uox|Itih2|Pzp|Plg|Cebpa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:267
Cell TypeLiver from male 3 month old
Gene Symbol (human)POR
Gene Symbol (mouse)Por
Organismmouse
Perturbation TypeDELETION
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM24728, GSM24729
Perturbed SamplesGSM24730, GSM24747
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1468
Gene Expression Omnibus
NADH-cytochrome P450 reductase deletion effect on liver
7
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