Interaction network and enrichment analysis of genes downregulated in MIR30A KD
Canned Analysis
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General Information
AccessionDCA00038841
TitleInteraction network and enrichment analysis of genes downregulated in MIR30A KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between MIR30A KD cells and control cells in the OvCa clear cell cell type.
Analysis URLhttp://genemania.org/#/search/human/RPS25|SNAR-A1|COL4A1|RPS10|LAMA5|EIF4A1|GNB2L1|RPS12|MMP7|SPINT2|FASN|RPL18|LAMC1|EZR|RPS2|FTL|LDLR|ALDH1A3|CDH1|RPL30|CLCN7|RPS11|RN7SL1|ACTB|RPL27A
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDgene:2697
Cell TypeOvCa clear cell
Gene Symbol (human)MIR30A
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM416663, GSM416664, GSM416665
Perturbed SamplesGSM416666, GSM416667, GSM416668
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16569
Gene Expression Omnibus
Gene expression analyses of mir-30a knockdown in ovarian clear cell cancer cell line
7
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