Interaction network and enrichment analysis of genes upregulated in TAF4B KO
Canned Analysis
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General Information
AccessionDCA00038846
TitleInteraction network and enrichment analysis of genes upregulated in TAF4B KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between TAF4B KO cells and control cells in the ovary cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Aldh1a1|Gas6|Rn28s1|Rn7sk|Igfbp5|Rny3|Tmem100|Sparcl1|Psap|Dcn|Col1a2|Apoe|Padi6|Soat1|Vim|Txnip|B2m|Igfbp7|Sparc|Cfh|Gm10925|Cyp11a1|Car3|Actg1|Serinc3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDgene:2699
Cell Typeovary
Gene Symbol (human)TAF4B
Gene Symbol (mouse)Taf4b
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM380314, GSM380315, GSM380316
Perturbed SamplesGSM380311, GSM380312, GSM380313
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15228
Gene Expression Omnibus
Gene expression differences between TAF4b-KO, Het and WT ovaries at 3 weeks of age
7
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