Interaction network and enrichment analysis of genes downregulated in ARNTL KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00038871
TitleInteraction network and enrichment analysis of genes downregulated in ARNTL KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between ARNTL KO cells and control cells in the dorsal skin basal interfollicular epidermal stem cells cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Hbb-b2|Hbb-bt|Hba-a2|Sprr2a2|Nr1d1|Ly6g6c|Ccnd2|Krt77|Dmkn|Gm94|Ahnak2|Iffo2|Slc6a6|Per3|Tns4|Fam25c|Krt10|Lgalsl|Igfbp3|Krt79|Dsg1b|Cd3g|Crabp2|H2-Ab1|Cyp2b10
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDgene:2710
Cell Typedorsal skin basal interfollicular epidermal stem cells
Gene Symbol (human)ARNTL
Gene Symbol (mouse)Arntl
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM668416, GSM668417, GSM668418
Perturbed SamplesGSM668419, GSM668420, GSM668421
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE27079
Gene Expression Omnibus
Expression data from epidermal stem cells isolated from dorsal skin of P19 Per1-Venus mice and Bmal1 epidermal knockout mice
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.