Interaction network and enrichment analysis of genes downregulated in SOX9 OE
Canned Analysis
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General Information
AccessionDCA00038901
TitleInteraction network and enrichment analysis of genes downregulated in SOX9 OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between SOX9 OE cells and control cells in the pancreas cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Bcl2a1d|Gimap4|Ptprc|Gm5771|H2-Ea-ps|H2-Aa|Trim30a|Hba-a2|Srgn|Reg3g|Fxyd5|Ifi203|Arhgdib|Igkv1-135|Iglv1|Cd28|Cd74|Ctss|C130026I21Rik|Faim3|Apbb1ip|Csprs|Hbb-bt|Hbb-b2|Coro1a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2743
Cell Typepancreas
Gene Symbol (human)SOX9
Gene Symbol (mouse)Sox9
Organismmouse
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM841168, GSM841169, GSM841170
Perturbed SamplesGSM841165, GSM841166, GSM841167
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34060
Gene Expression Omnibus
Sox9+ pancreatic cells: developmental time course
7
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