Interaction network and enrichment analysis of genes downregulated in MMP7 KO
Canned Analysis
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General Information
AccessionDCA00038909
TitleInteraction network and enrichment analysis of genes downregulated in MMP7 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between MMP7 KO cells and control cells in the epithelium cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Mgp|Spp1|Supt16|Gm3776|Ptplad2|Rnu7|Ctss|Pam|Rab5c|Tinag|Gm14434|Gm4354|Pkhd1|Zfp551|Irf2|C1qa|6820431F20Rik|Snord104|Dapl1|Mki67|Csrnp2|Apoe|Zbtb38|D130051D11Rik|Snhg3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2747
Cell Typeepithelium
Gene Symbol (human)MMP7
Gene Symbol (mouse)Mmp7
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM196062, GSM196063, GSM196064
Perturbed SamplesGSM196070, GSM196071, GSM196072
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE7957
Gene Expression Omnibus
Matrix metalloproteinase mutant airway epithelial cells response to Pseudomonas aeruginosa infection: time course
14
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