Interaction network and enrichment analysis of genes upregulated in PAGE5 KD
Canned Analysis
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General Information
AccessionDCA00038916
TitleInteraction network and enrichment analysis of genes upregulated in PAGE5 KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between PAGE5 KD cells and control cells in the A2058 cell type.
Analysis URLhttp://genemania.org/#/search/human/RPS27|RPS21|RPL11|RPL18A|RPL23A|ACTB|FAM98B|RPS20|RPL31|RPL23|UBB|HSP90AA1|UBC|ATP5E|KBTBD6|ZNF91|SLC7A11|RPL21|RPS17|RPS27A|RPS25|HSPE1|SLFN13|TIMP1|MYL6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorApozar
CREEDS IDgene:2752
Cell TypeA2058
Gene Symbol (human)PAGE5
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM777484, GSM777486, GSM777488
Perturbed SamplesGSM777485, GSM777487, GSM777489
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31351
Gene Expression Omnibus
Transcriptomic analysis of the effect of CT16 (PAGE5) silencing by RNAi in A2058 melanoma cells
7
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