Interaction network and enrichment analysis of genes upregulated in VLDLR KO
Canned Analysis
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General Information
AccessionDCA00038950
TitleInteraction network and enrichment analysis of genes upregulated in VLDLR KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between VLDLR KO cells and control cells in the lung cell type.
Analysis URLhttp://genemania.org/#/search/mouse/LOC637260|Igh-VX24|BC018473|Ighg3|Lyz1|Chil1|1700047I17Rik2|Gp2|Lcn2|Ighm|Mt2|Gm10653|V165-D-J-C mu|Ighv1-72|Rps2|Muc5b|Igkv6-23|1810032O08Rik|Dusp1|Lbp|Plet1|Rpl34-ps1|Igkv8-19|Cd209a|Igkv4-91
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorasingh
CREEDS IDgene:2777
Cell Typelung
Gene Symbol (human)VLDLR
Gene Symbol (mouse)Vldlr
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1332383, GSM1332384, GSM1332385, GSM1332386
Perturbed SamplesGSM1332387, GSM1332388, GSM1332389, GSM1332390
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE55247
Gene Expression Omnibus
Very low density lipoprotein receptor knockout effect in house dust mite model of asthma: lung
7
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