Interaction network and enrichment analysis of genes upregulated in MBD1 KO
Canned Analysis
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General Information
AccessionDCA00039060
TitleInteraction network and enrichment analysis of genes upregulated in MBD1 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between MBD1 KO cells and control cells in the thymus cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Nfkbia|Cd74|Ccl25|Lars2|Hist1h4f|Rplp1|Ndufc2|Hist1h4a|Rn28s1|Laptm5|Ngfrap1|Rps16|Sri|Atp5e|Rpl41|Rpl23a|Hist1h2ao|S100a16|Rplp2|Ly6e|Hist1h4d|H2-D1|Tpt1|Alox12e|Hist1h3d
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorTolen
CREEDS IDgene:2835
Cell Typethymus
Gene Symbol (human)MBD1
Gene Symbol (mouse)Mbd1
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1269608, GSM1269609, GSM1269610
Perturbed SamplesGSM1269611, GSM1269612, GSM1269613
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52547
Gene Expression Omnibus
Medullary Thymic Epitherlial Cell (mTEC) Gene Expression in MBD1 WT and KO Mice
7
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