Interaction network and enrichment analysis of genes upregulated in SRF KO
Canned Analysis
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General Information
AccessionDCA00039142
TitleInteraction network and enrichment analysis of genes upregulated in SRF KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between SRF KO cells and control cells in the aorta cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Ly6a|Hba-a2|Mgp|Serping1|Cst3|Hbb-bs|Cytl1|Ifitm3|Dpt|Cfh|Gm1821|B2m|Rps27rt|Rps12|Ppap2b|Tmsb4x|Rpl10|Mustn1|Rps28|Ly6c2|Crispld2|Col6a3|Vwf|Rpl18a|Rplp1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2884
Cell Typeaorta
Gene Symbol (human)SRF
Gene Symbol (mouse)Srf
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM850855, GSM850856, GSM850859, GSM850860
Perturbed SamplesGSM850857, GSM850858, GSM850861, GSM850862
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE34545
Gene Expression Omnibus
Early effects of Serum Response Factor (SRF) gene deletion on the vascular gene expression
7
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