Interaction network and enrichment analysis of genes downregulated in POU1F1 OE
Canned Analysis
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General Information
AccessionDCA00039221
TitleInteraction network and enrichment analysis of genes downregulated in POU1F1 OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between POU1F1 OE cells and control cells in the MCF-7 breast adenocarcinoma cell line cell type.
Analysis URLhttp://genemania.org/#/search/human/RPL7|SNORD15B|SNORA31|RPS3A|RPL9|RNU2-2P|RNU1-1|SNORA57|HIST1H4D|HIST1H2AC|USMG5|HIST1H1B|BAGE|RPS20|SNORA10|SNORA60|SNORD3D|MIR1307|RPL17|MSX2|SNORA23|RPS3|TM4SF1|SNORD43|SNORD74
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2931
Cell TypeMCF-7 breast adenocarcinoma cell line
Gene Symbol (human)POU1F1
Gene Symbol (mouse)Pou1f1
Organismhuman
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1564340, GSM1564341
Perturbed SamplesGSM1564342, GSM1564343
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE64101
Gene Expression Omnibus
Pit-1 overexpression in the human breast adenocarcinoma MCF-7 cell line
7
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