Interaction network and enrichment analysis of genes upregulated in BRMS1 KD
Canned Analysis
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General Information
AccessionDCA00039224
TitleInteraction network and enrichment analysis of genes upregulated in BRMS1 KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between BRMS1 KD cells and control cells in the NSCLC (non-samll cell lung cancer) H1993 cells cell type.
Analysis URLhttp://genemania.org/#/search/human/MT2A|MT1A|TGFBI|LGALS1|SLC16A3|VIM|CXCL8|MT1X|PRICKLE1|MMP1|GNAS|ENO1|IGF2R|OAZ1|AP2S1|BNIP3|RPL17|RPL35A|RPL31|B2M|GSTO1|DDIT4|FHL2|MYL12A|ATP5EP2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2935
Cell TypeNSCLC (non-samll cell lung cancer) H1993 cells
Gene Symbol (human)BRMS1
Gene Symbol (mouse)Brms1
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1525721, GSM1525722
Perturbed SamplesGSM1525719, GSM1525720
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE62359
Gene Expression Omnibus
Loss of BRMS1 promotes a mesenchymal phenotype through regulation of Twist1
7
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